HPV Vaccination –

Q 1 What  are the types of HPV  vaccination ?

Approximately -100 types of HPV virus  have been identified ,at least 40 of which affect genital areas

1.Cervarix  Vaccine-

• Bivalent HPV  vaccine gives protection against HPV 16,18  virus
• 98% protection against CIN 2+ (cervical intraepithelial neoplasia)
• 10 to 45 yrs
• Dose-0, 1 , 6 months
• Pure cervical cancer vaccine

2.  Gardasil  Vaccine -

• Quadrivalent   HPV vaccine gives protection against HPV   16,18, 6, 11 virus
• 6 ,11 non oncogenic
• 98% protection against CIN 2+(cervical intraepithelial neoplasia) & ( 100% against VAIN,(vaginal intraepithelial lesion ) VIN, ( vulval intraepithelial neoplasia) genital warts
• 9 to 45 years
• Dose-0,2, 6 ,months
• Dual cervical cancer and genital warts vaccine

Q 2    What are the recommendations and whom should be given HPV vaccination ?

• Routine vaccination-10-12 years females, minimum age of vaccination is : 9 years may be offered upto 45 years
• No evidence to support use of booster
• Can be given in women previously exposed or treated- protects against other genotypes
• Routine screening to be done post-vaccination
• No recommendation for HPV testing prior to immunisation
• Contraindicated-pregnancy; safe in lactation